OriginTrail is an ecosystem dedicated to making the global economy work sustainably by organizing humanity’s most important knowledge assets. It leverages the open source Decentralized Knowledge Graph that connects the physical world (art, healthcare, fashion, education, supply chains, ...) and the digital world (blockchain, smart contracts, Metaverse & NFTs, …) in a single connected reality driving transparency and trust. Advanced knowledge graph technology currently powers trillion-dollar companies like Google and Facebook. By reshaping it for Web3, the OriginTrail Decentralized Knowledge Graph provides a crucial fabric to link, verify, and value data on both physical and digital assets. World class companies are already using OriginTrail to create value for their ecosystems. For example, OriginTrail is enabling frictionless international trade for over 40% of US imports by fostering secure exchange of security audits. The same semantic fabric of the decentralized knowledge graph protects pharmaceutical supply chains or can be used to organize blockchain data for seamless access by decentralized applications (e.g. Metaverses).